A nicotine
patch worn for six months can improve attention, memory and mental
processing in people with mild cognitive impairment, a clinical trial
has found.
Researchers randomly assigned 67 otherwise healthy men and women with
M.C.I. to wear a nicotine patch or a placebo patch for six months. The
volunteers, nonsmokers whose average age was 76, took periodic tests of
mental ability, mood and behavior.
Those with the nicotine patch showed improvements in reaction times,
attention and long-term memory, and more modest improvements in
short-term memory. For subjects on the placebo, scores declined on those
tests.
Mild cognitive impairment, or M.C.I., involves a decline in mental
acuity that is noticeable but not severe enough to be diagnosed as dementia. It is often a precursor to more severe disease.
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